Drugs & Vitamins

Paliperidone extended-release tablets Active Ingredients: Paliperidone extended-release tablets Representative Names: Invega Available Product Images: What are Paliperidone extended-release tablets? What should I tell my health care provider before I take this medicine? How should this medicine be used? What if I miss a dose? What drug(s) may interact with Paliperidone? What side effects may I notice from receiving Paliperidone? What should I watch for while taking Paliperidone? Where can I keep my medicine? What are Paliperidone extended-release tablets? (Back to top) PALIPERIDONE is used to treat schizophrenia. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •blood disorder or disease •dementia •diabetes or family history of diabetes •difficulty swallowing •heart disease or previous heart attack •history of brain tumor or head injury •history of breast cancer •history of stroke •irregular heart beat or low blood pressure •kidney disease •liver disease •Parkinson's disease •seizures (convulsions) •an unusual reaction to paliperidone, other medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should this medicine be used? (Back to top) Take this medicine by mouth. Follow the directions on the prescription label. Swallow the tablets whole with a drink of water. Do not crush, divide, or chew the tablets. You can take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your prescriber's advice. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. What drug(s) may interact with Paliperidone? (Back to top) •abarelix •alcohol •arsenic trioxide •astemizole •bromocriptine •cabergoline •cisapride •clarithromycin •droperidol •erythromycin •halofantrine •levodopa and other medications for Parkinson's disease •levomethadyl •medicines for anxiety, depression or psychotic disturbances •medicines for diabetes •medicines for high blood pressure •medicines for irregular heartbeats •medicines for treating seizures (convulsions) •medicines for sleep or sedation •pentamidine •prescription pain medications •probucol •some antibiotics for treating infections (gatifloxacin, levofloxacin, moxifloxacin, sparfloxacin) •some medicines for the hormonal treatment of cancer •terfenadine Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from receiving Paliperidone? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: •changes in vision •confusion •fainting spells •fast or irregular heartbeat •increased thirst or hunger •increased need to pass urine •inner restlessness, unable to keep still •loss of balance, difficulty walking or falls •stiffness, spasms, trembling Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •cough •decreased sexual ability •drowsiness or dizziness •headache •increase or decrease in saliva •menstrual irregularity •nausea, vomiting •stomach pain •unusual tiredness •weight gain What should I watch for while taking Paliperidone? (Back to top) Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of this medicine. Do not suddenly stop taking the medicine. You may need to gradually reduce the dose. Only stop taking your medicine on your doctor's advice. You may become overheated more easily while taking this medicine. Excess exercise, dehydration (lack of water), or extreme heat may worsen this condition. The outer tablet shell of this medicine does not dissolve in the body. Do not be concerned if you notice the tablet shell and other tablet ingredients in your stool when you go to the bathroom. This does not affect the medicine or how well it is working. You may get dizzy or drowsy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase dizziness and drowsiness. Avoid alcoholic drinks. Where can I keep my medicine? (Back to top) Keep out of the reach of children. Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date. Last Updated:01/31/2007 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.